Definition of "major league"

An association of sports teams which plays at the highest skill level of its sport, especially Major League Baseball.  examples

(usually in plural or attributive) The highest level of competition in a field of endeavor.  examples

Of or pertaining to a major sports league; belonging to the professional level of a sport, such as US baseball.  examples

Analogous in importance to a major league sports team.  examples

Serious, high-level; significant  examples